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Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection
Cytokine storm during viral infection is a prospective predictor of morbidity and mortality, yet the cellular sources remain undefined. Here, using genetic and chemical tools to probe functions of the S1P(1) receptor, we elucidate cellular and signaling mechanisms that are important in initiating cy...
Autores principales: | Teijaro, John R., Walsh, Kevin B., Cahalan, Stuart, Fremgen, Daniel M., Roberts, Edward, Scott, Fiona, Martinborough, Esther, Peach, Robert, Oldstone, Michael B.A., Rosen, Hugh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176439/ https://www.ncbi.nlm.nih.gov/pubmed/21925319 http://dx.doi.org/10.1016/j.cell.2011.08.015 |
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