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An essential protective role of IL-10 in the immunological mechanism underlying resistance vs susceptibility to lupus induction by dendritic cells and dying cells

Objective. To define the role of IL-10 in lupus pathogenesis, and to understand the immunological mechanisms underlying resistance vs susceptibility to lupus disease induction by dendritic cells (DCs) and dying cells. Methods. Groups of IL-10-deficient and normal C57BL/6 mice were injected with syng...

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Detalles Bibliográficos
Autores principales: Ling, Guang-Sheng, Cook, H. Terence, Botto, Marina, Lau, Yu-Lung, Huang, Fang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176714/
https://www.ncbi.nlm.nih.gov/pubmed/21727182
http://dx.doi.org/10.1093/rheumatology/ker198