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High Resolution Analysis of the Chromatin Landscape of the IgE Switch Region in Human B Cells

Antibodies are assembled by a highly orchestrated series of recombination events during B cell development. One of these events, class switch recombination, is required to produce the IgG, IgE and IgA antibody isotypes characteristic of a secondary immune response. The action of the enzyme activatio...

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Detalles Bibliográficos
Autores principales: Dayal, Sandeep, Nedbal, Jakub, Hobson, Philip, Cooper, Alison M., Gould, Hannah J., Gellert, Martin, Felsenfeld, Gary, Fear, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176761/
https://www.ncbi.nlm.nih.gov/pubmed/21949728
http://dx.doi.org/10.1371/journal.pone.0024571