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High Resolution Analysis of the Chromatin Landscape of the IgE Switch Region in Human B Cells
Antibodies are assembled by a highly orchestrated series of recombination events during B cell development. One of these events, class switch recombination, is required to produce the IgG, IgE and IgA antibody isotypes characteristic of a secondary immune response. The action of the enzyme activatio...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176761/ https://www.ncbi.nlm.nih.gov/pubmed/21949728 http://dx.doi.org/10.1371/journal.pone.0024571 |