Noninvasive Assessment of Antenatal Hydronephrosis in Mice Reveals a Critical Role for Robo2 in Maintaining Anti-Reflux Mechanism

Antenatal hydronephrosis and vesicoureteral reflux (VUR) are common renal tract birth defects. We recently showed that disruption of the Robo2 gene is associated with VUR in humans and antenatal hydronephrosis in knockout mice. However, the natural history, causal relationship and developmental orig...

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Detalles Bibliográficos
Autores principales: Wang, Hang, Li, Qinggang, Liu, Juan, Mendelsohn, Cathy, Salant, David J., Lu, Weining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176762/
https://www.ncbi.nlm.nih.gov/pubmed/21949750
http://dx.doi.org/10.1371/journal.pone.0024763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176762/
https://www.ncbi.nlm.nih.gov/pubmed/21949750
http://dx.doi.org/10.1371/journal.pone.0024763

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