RNA Oxidation Adducts 8-OHG and 8-OHA Change with Aβ(42) Levels in Late-Stage Alzheimer's Disease

While research supports amyloid-β (Aβ) as the etiologic agent of Alzheimer's disease (AD), the mechanism of action remains unclear. Evidence indicates that adducts of RNA caused by oxidation also represent an early phenomenon in AD. It is currently unknown what type of influence these two obser...

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Detalles Bibliográficos
Autores principales: Weidner, Adam M., Bradley, Melissa A., Beckett, Tina L., Niedowicz, Dana M., Dowling, Amy L. S., Matveev, Sergey V., LeVine, Harry, Lovell, Mark A., Murphy, M. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176793/
https://www.ncbi.nlm.nih.gov/pubmed/21949792
http://dx.doi.org/10.1371/journal.pone.0024930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176793/
https://www.ncbi.nlm.nih.gov/pubmed/21949792
http://dx.doi.org/10.1371/journal.pone.0024930

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