Homozygosity Mapping on Homozygosity Haplotype Analysis to Detect Recessive Disease-Causing Genes from a Small Number of Unrelated, Outbred Patients

Genes involved in disease that are not common are often difficult to identify; a method that pinpoints them from a small number of unrelated patients will be of great help. In order to establish such a method that detects recessive genes identical-by-descent, we modified homozygosity mapping (HM) so...

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Detalles Bibliográficos
Autores principales: Hagiwara, Koichi, Morino, Hiroyuki, Shiihara, Jun, Tanaka, Tomoaki, Miyazawa, Hitoshi, Suzuki, Tomoko, Kohda, Masakazu, Okazaki, Yasushi, Seyama, Kuniaki, Kawakami, Hideshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176806/
https://www.ncbi.nlm.nih.gov/pubmed/21949849
http://dx.doi.org/10.1371/journal.pone.0025059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176806/
https://www.ncbi.nlm.nih.gov/pubmed/21949849
http://dx.doi.org/10.1371/journal.pone.0025059

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