TGFBR2 and BAX Mononucleotide Tract Mutations, Microsatellite Instability, and Prognosis in 1072 Colorectal Cancers

BACKGROUND: Mononucleotide tracts in the coding regions of the TGFBR2 and BAX genes are commonly mutated in microsatellite instability-high (MSI-high) colon cancers. The receptor TGFBR2 plays an important role in the TGFB1 (transforming growth factor-β, TGF-β) signaling pathway, and BAX plays a key...

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Detalles Bibliográficos
Autores principales: Shima, Kaori, Morikawa, Teppei, Yamauchi, Mai, Kuchiba, Aya, Imamura, Yu, Liao, Xiaoyun, Meyerhardt, Jeffrey A., Fuchs, Charles S., Ogino, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176811/
https://www.ncbi.nlm.nih.gov/pubmed/21949851
http://dx.doi.org/10.1371/journal.pone.0025062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176811/
https://www.ncbi.nlm.nih.gov/pubmed/21949851
http://dx.doi.org/10.1371/journal.pone.0025062

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