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Type III Nrg1 Back Signaling Enhances Functional TRPV1 along Sensory Axons Contributing to Basal and Inflammatory Thermal Pain Sensation

Type III Nrg1, a member of the Nrg1 family of signaling proteins, is expressed in sensory neurons, where it can signal in a bi-directional manner via interactions with the ErbB family of receptor tyrosine kinases (ErbB RTKs) [1]. Type III Nrg1 signaling as a receptor (Type III Nrg1 back signaling) c...

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Detalles Bibliográficos
Autores principales: Canetta, Sarah E., Luca, Edlira, Pertot, Elyse, Role, Lorna W., Talmage, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176819/
https://www.ncbi.nlm.nih.gov/pubmed/21949864
http://dx.doi.org/10.1371/journal.pone.0025108