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The Y-Encoded Gene Zfy2 Acts to Remove Cells with Unpaired Chromosomes at the First Meiotic Metaphase in Male Mice

During male but not female mammalian meiosis, there is efficient apoptotic elimination of cells with unpaired (univalent) chromosomes at the first meiotic metaphase (MI) [1]. Apoptotic elimination of MI spermatocytes is seen in response to the univalent X chromosome of XSxr(a)O male mice [2], in whi...

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Detalles Bibliográficos
Autores principales: Vernet, Nadège, Mahadevaiah, Shantha K., Ojarikre, Obah A., Longepied, Guy, Prosser, Haydn M., Bradley, Allan, Mitchell, Michael J., Burgoyne, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176893/
https://www.ncbi.nlm.nih.gov/pubmed/21530259
http://dx.doi.org/10.1016/j.cub.2011.03.057