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The Y-Encoded Gene Zfy2 Acts to Remove Cells with Unpaired Chromosomes at the First Meiotic Metaphase in Male Mice
During male but not female mammalian meiosis, there is efficient apoptotic elimination of cells with unpaired (univalent) chromosomes at the first meiotic metaphase (MI) [1]. Apoptotic elimination of MI spermatocytes is seen in response to the univalent X chromosome of XSxr(a)O male mice [2], in whi...
Autores principales: | Vernet, Nadège, Mahadevaiah, Shantha K., Ojarikre, Obah A., Longepied, Guy, Prosser, Haydn M., Bradley, Allan, Mitchell, Michael J., Burgoyne, Paul S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176893/ https://www.ncbi.nlm.nih.gov/pubmed/21530259 http://dx.doi.org/10.1016/j.cub.2011.03.057 |
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