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Targeting HDACs: A Promising Therapy for Alzheimer's Disease

Epigenetic modifications like DNA methylation and histone acetylation play an important role in a wide range of brain disorders. Histone deacetylases (HDACs) regulate the homeostasis of histone acetylation. Histone deacetylase inhibitors, which initially were used as anticancer drugs, are recently s...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Dai, Xue-Ling, Huang, Han-Chang, Jiang, Zhao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177096/
https://www.ncbi.nlm.nih.gov/pubmed/21941604
http://dx.doi.org/10.1155/2011/143269