The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes

The ultimate step common to almost all DNA repair pathways is the ligation of the nicked intermediate to form contiguous double-stranded DNA. In the mammalian nucleotide and base excision repair pathways, the ligation step is carried out by ligase III-α. For efficient ligation, ligase III-α is const...

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Detalles Bibliográficos
Autores principales: Cuneo, Matthew J., Gabel, Scott A., Krahn, Joseph M., Ricker, Melissa A., London, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177190/
https://www.ncbi.nlm.nih.gov/pubmed/21652643
http://dx.doi.org/10.1093/nar/gkr419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177190/
https://www.ncbi.nlm.nih.gov/pubmed/21652643
http://dx.doi.org/10.1093/nar/gkr419

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