Cargando…

The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes

The ultimate step common to almost all DNA repair pathways is the ligation of the nicked intermediate to form contiguous double-stranded DNA. In the mammalian nucleotide and base excision repair pathways, the ligation step is carried out by ligase III-α. For efficient ligation, ligase III-α is const...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cuneo, Matthew J., Gabel, Scott A., Krahn, Joseph M., Ricker, Melissa A., London, Robert E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177190/ https://www.ncbi.nlm.nih.gov/pubmed/21652643 http://dx.doi.org/10.1093/nar/gkr419

Ejemplares similares

An atypical BRCT–BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex
por: Hammel, Michal, et al.
Publicado: (2020)

Structural studies of the PARP-1 BRCT domain
por: Loeffler, Paul A, et al.
Publicado: (2011)

Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation
por: Zheng, Xunhai, et al.
Publicado: (2014)

Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain
por: Cheng, Xiankun, et al.
Publicado: (2019)

Structural basis for the cooperative DNA recognition by Smad4 MH1 dimers
por: Baburajendran, Nithya, et al.
Publicado: (2011)

A human XRCC4–XLF complex bridges DNA
por: Andres, Sara N., et al.
Publicado: (2012)

Structural and functional characterization of the PNKP–XRCC4–LigIV DNA repair complex
por: Aceytuno, R. Daniel, et al.
Publicado: (2017)

Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR–Cas12f nuclease
por: Xiao, Renjian, et al.
Publicado: (2021)

Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1
por: Knott, Gavin J, et al.
Publicado: (2021)

Structural basis for inhibition of the type I-F CRISPR–Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14
por: Gabel, Clinton, et al.
Publicado: (2020)

Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes
por: Moon, Andrea F., et al.
Publicado: (2016)

Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites
por: Wu, Qian, et al.
Publicado: (2016)

Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK
por: Ali, Ammar A. E., et al.
Publicado: (2009)

Structure of mitochondrial poly(A) RNA polymerase reveals the structural basis for dimerization, ATP selectivity and the SPAX4 disease phenotype
por: Lapkouski, Mikalai, et al.
Publicado: (2015)

Structural asymmetry in the Thermus thermophilus RuvC dimer suggests a basis for sequential strand cleavages during Holliday junction resolution
por: Chen, Luan, et al.
Publicado: (2013)

Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases
por: Molina, Rafael, et al.
Publicado: (2021)

T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction
por: Shi, Ke, et al.
Publicado: (2018)

Structural basis for the dimerization of Nab2 generated by RNA binding provides insight into its contribution to both poly(A) tail length determination and transcript compaction in Saccharomyces cerevisiae
por: Aibara, Shintaro, et al.
Publicado: (2017)

Molecular basis of stepwise cyclic tetra-adenylate cleavage by the type III CRISPR ring nuclease Crn1/Sso2081
por: Du, Liyang, et al.
Publicado: (2023)

Structural basis for translation termination by archaeal RF1 and GTP-bound EF1α complex
por: Kobayashi, Kan, et al.
Publicado: (2012)

Structure of an inactive RNA polymerase II dimer
por: Aibara, Shintaro, et al.
Publicado: (2021)

DNA i-motif formation at neutral pH is driven by kinetic partitioning
por: Školáková, Petra, et al.
Publicado: (2023)

Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography
por: Davies, Karen M., et al.
Publicado: (2014)

Solution structure of Domains IVa and V of the τ subunit of Escherichia coli DNA polymerase III and interaction with the α subunit
por: Su, Xun-Cheng, et al.
Publicado: (2007)

p38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage
por: de Sousa, Mirta Mittelstedt Leal, et al.
Publicado: (2017)

Crystal structure of an intermediate of rotating dimers within the synaptic tetramer of the G-segment invertase
por: Ritacco, Christopher J., et al.
Publicado: (2013)

Crucial roles for DNA ligase III in mitochondria but not in XRCC1-dependent repair
por: Simsek, Deniz, et al.
Publicado: (2011)

Structural basis of σ appropriation
por: Shi, Jing, et al.
Publicado: (2019)

Alternative dimerization is required for activity and inhibition of the HEPN ribonuclease RnlA
por: Garcia-Rodriguez, Gabriela, et al.
Publicado: (2021)

DNA binding with a minimal scaffold: structure–function analysis of Lig E DNA ligases
por: Williamson, Adele, et al.
Publicado: (2018)

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments
por: Tang, Shaogeng, et al.
Publicado: (2015)

Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206
por: Liang, Yu, et al.
Publicado: (2012)

Structural insights into the dimerization of the response regulator ComE from Streptococcus pneumoniae
por: Boudes, Marion, et al.
Publicado: (2014)

Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA
por: Tamulaitiene, Giedre, et al.
Publicado: (2017)

Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA
por: Patel, Abdul Kareem Mohideen, et al.
Publicado: (2023)

DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions
por: Chen, Yongheng, et al.
Publicado: (2015)

Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major
por: Meleppattu, Shimi, et al.
Publicado: (2018)

Structural basis for cloverleaf RNA-initiated viral genome replication
por: Gottipati, Keerthi, et al.
Publicado: (2023)

Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase
por: Gondeau, C., et al.
Publicado: (2008)

Structure of CRL2(Lrr1), the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates
por: Zhou, Haixia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bb3jg26gd8ao9nk5j5shqhk46p