Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase

The development of new methods for gene addition to mammalian genomes is necessary to overcome the limitations of conventional genetic engineering strategies. Although a variety of DNA-modifying enzymes have been used to directly catalyze the integration of plasmid DNA into mammalian genomes, there...

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Detalles Bibliográficos
Autores principales: Gersbach, Charles A., Gaj, Thomas, Gordley, Russell M., Mercer, Andrew C., Barbas, Carlos F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177191/
https://www.ncbi.nlm.nih.gov/pubmed/21653554
http://dx.doi.org/10.1093/nar/gkr421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177191/
https://www.ncbi.nlm.nih.gov/pubmed/21653554
http://dx.doi.org/10.1093/nar/gkr421

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