Cargando…
Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase
The development of new methods for gene addition to mammalian genomes is necessary to overcome the limitations of conventional genetic engineering strategies. Although a variety of DNA-modifying enzymes have been used to directly catalyze the integration of plasmid DNA into mammalian genomes, there...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177191/ https://www.ncbi.nlm.nih.gov/pubmed/21653554 http://dx.doi.org/10.1093/nar/gkr421 |