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miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components

In animals, microRNAs (miRNAs) generally repress gene expression by binding to sites in the 3′-untranslated region (UTR) of target mRNAs. miRNAs have also been reported to repress or activate gene expression by binding to 5′-UTR sites, but the extent of such regulation and the factors that govern th...

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Detalles Bibliográficos
Autores principales: Roberts, Ashley P. E., Lewis, Andrew P., Jopling, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177192/
https://www.ncbi.nlm.nih.gov/pubmed/21653556
http://dx.doi.org/10.1093/nar/gkr426