Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases

DNA interstrand crosslinks (ICLs), inhibit DNA metabolism by covalently linking two strands of DNA and are formed by antitumor agents such as cisplatin and nitrogen mustards. Multiple complex repair pathways of ICLs exist in humans that share translesion synthesis (TLS) past a partially processed IC...

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Bibliografische gegevens
Hoofdauteurs: Ho, The Vinh, Guainazzi, Angelo, Derkunt, Semsi Burak, Enoiu, Milica, Schärer, Orlando D.
Formaat: Online Artikel Texto
Taal:English
Gepubliceerd in: Oxford University Press 2011
Onderwerpen:
Genome Integrity, Repair and Replication
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177197/
https://www.ncbi.nlm.nih.gov/pubmed/21666254
http://dx.doi.org/10.1093/nar/gkr448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177197/
https://www.ncbi.nlm.nih.gov/pubmed/21666254
http://dx.doi.org/10.1093/nar/gkr448

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