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Concerted action at eight phosphodiester bonds by the BcgI restriction endonuclease

The BcgI endonuclease exemplifies a subset of restriction enzymes, the Type IIB class, which make two double-strand breaks (DSBs) at each copy of their recognition sequence, one either side of the site, to excise the sequence from the remainder of the DNA. In this study, we show that BcgI is essenti...

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Detalles Bibliográficos
Autores principales: Marshall, Jacqueline J. T., Smith, Rachel M., Ganguly, Sumita, Halford, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177199/
https://www.ncbi.nlm.nih.gov/pubmed/21653548
http://dx.doi.org/10.1093/nar/gkr453