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Overlapping signals for translational regulation and packaging of influenza A virus segment 2

Influenza A virus segment 2 mRNA expresses three polypeptides: PB1, PB1-F2 and PB1-N40, from AUGs 1, 4 and 5 respectively. Two short open reading frames (sORFs) initiated by AUGs 2 and 3 are also present. To understand translational regulation in this system, we systematically mutated AUGs 1–4 and m...

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Detalles Bibliográficos
Autores principales: Wise, Helen M., Barbezange, Cyril, Jagger, Brett W., Dalton, Rosa M., Gog, Julia R., Curran, Martin D., Taubenberger, Jeffery K., Anderson, Emma C., Digard, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177217/
https://www.ncbi.nlm.nih.gov/pubmed/21693560
http://dx.doi.org/10.1093/nar/gkr487