Efficient gene targeting mediated by a lentiviral vector-associated meganuclease

Gene targeting can be achieved with lentiviral vectors delivering donor sequences along with a nuclease that creates a locus-specific double-strand break (DSB). Therapeutic applications of this system would require an appropriate control of the amount of endonuclease delivered to the target cells, a...

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Detalles Bibliográficos
Autores principales: Izmiryan, Araksya, Basmaciogullari, Stéphane, Henry, Adrien, Paques, Frédéric, Danos, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177226/
https://www.ncbi.nlm.nih.gov/pubmed/21715375
http://dx.doi.org/10.1093/nar/gkr524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177226/
https://www.ncbi.nlm.nih.gov/pubmed/21715375
http://dx.doi.org/10.1093/nar/gkr524

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