Photoswitching of Site-Selective RNA Scission by Sequential Incorporation of Azobenzene and Acridine Residues in a DNA Oligomer

Photoresponsive systems for site-selective RNA scission have been prepared by combining Lu(III) ions with acridine/azobenzene dual-modified DNA. The modified DNA forms a heteroduplex with substrate RNA, and the target phosphodiester linkages in front of the acridine residue is selectively activated...

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Detalles Bibliográficos
Autores principales: Kuzuya, Akinori, Tanaka, Keita, Komiyama, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177363/
https://www.ncbi.nlm.nih.gov/pubmed/21941627
http://dx.doi.org/10.4061/2011/162452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177363/
https://www.ncbi.nlm.nih.gov/pubmed/21941627
http://dx.doi.org/10.4061/2011/162452

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