Bromodomains as therapeutic targets

Acetylation of lysine residues is a post-translational modification with broad relevance to cellular signalling and disease biology. Enzymes that ‘write’ (histone acetyltransferases, HATs) and ‘erase’ (histone deacetylases, HDACs) acetylation sites are an area of extensive research in current drug d...

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Detalles Bibliográficos
Autores principales: Muller, Susanne, Filippakopoulos, Panagis, Knapp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177561/
https://www.ncbi.nlm.nih.gov/pubmed/21933453
http://dx.doi.org/10.1017/S1462399411001992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177561/
https://www.ncbi.nlm.nih.gov/pubmed/21933453
http://dx.doi.org/10.1017/S1462399411001992

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