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Anti-DLL4, a cancer therapeutic with multiple mechanisms of action

DLL4 is a ligand for the Notch family of receptors. DLL4 has many important functions in normal development and tissue homeostasis, including roles in the immune system, the gastro-intestinal tract, and in vascular development. Because of the importance of Notch signaling in stem cell biology, DLL4...

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Detalles Bibliográficos
Autores principales: Gurney, Austin, Hoey, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177777/
https://www.ncbi.nlm.nih.gov/pubmed/21831306
http://dx.doi.org/10.1186/2045-824X-3-18