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Anti-DLL4, a cancer therapeutic with multiple mechanisms of action
DLL4 is a ligand for the Notch family of receptors. DLL4 has many important functions in normal development and tissue homeostasis, including roles in the immune system, the gastro-intestinal tract, and in vascular development. Because of the importance of Notch signaling in stem cell biology, DLL4...
Autores principales: | Gurney, Austin, Hoey, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177777/ https://www.ncbi.nlm.nih.gov/pubmed/21831306 http://dx.doi.org/10.1186/2045-824X-3-18 |
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