Polymorphisms in melatonin synthesis pathways: possible influences on depression

BACKGROUND: It has been reported that rs4446909, a single nucleotide polymorphism (SNP) in the promoter of acetylserotonin methyltransferase (ASMT), influences the expression of the ASMT enzyme. The common G allele is associated with lower ASMT activity, and therefore, diminishes conversion of N-ace...

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Detalles Bibliográficos
Autores principales: Kripke, Daniel F, Nievergelt, Caroline M, Tranah, Greg J, Murray, Sarah S, McCarthy, Michael J, Rex, Katharine M, Parimi, Neeta, Kelsoe, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177871/
https://www.ncbi.nlm.nih.gov/pubmed/21827647
http://dx.doi.org/10.1186/1740-3391-9-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177871/
https://www.ncbi.nlm.nih.gov/pubmed/21827647
http://dx.doi.org/10.1186/1740-3391-9-8

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