Anticancer Effects of 15d-Prostaglandin-J(2) in Wild-Type and Doxorubicin-Resistant Ovarian Cancer Cells: Novel Actions on SIRT1 and HDAC

15-deoxy-delta-12,14-prostaglandin-J(2) (15d-PGJ(2)), an arachidonic metabolite and a natural PPARγ agonist, is known to induce apoptosis in tumor cells. In this study, we investigated new therapeutic potentials of 15d-PGJ(2) by determining its anticancer effects in wild-type and doxorubicin-resista...

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Detalles Bibliográficos
Autores principales: de Jong, Edwin, Winkel, Peter, Poelstra, Klaas, Prakash, Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177888/
https://www.ncbi.nlm.nih.gov/pubmed/21957481
http://dx.doi.org/10.1371/journal.pone.0025192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177888/
https://www.ncbi.nlm.nih.gov/pubmed/21957481
http://dx.doi.org/10.1371/journal.pone.0025192

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