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The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat

BACKGROUND: Tumour necrosis factor-α (TNF-α) is a pleiotropic pro-inflammatory cytokine, which is rapidly upregulated in the brain after injury. TNF-α acts by binding to its receptors, TNF-R1 (p55) and TNF-R2 (p75), on the cell surface. The aim of this study was first to investigate if there is alte...

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Detalles Bibliográficos
Autores principales: Maddahi, Aida, Kruse, Lars S, Chen, Qing-Wen, Edvinsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177895/
https://www.ncbi.nlm.nih.gov/pubmed/21871121
http://dx.doi.org/10.1186/1742-2094-8-107