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The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat
BACKGROUND: Tumour necrosis factor-α (TNF-α) is a pleiotropic pro-inflammatory cytokine, which is rapidly upregulated in the brain after injury. TNF-α acts by binding to its receptors, TNF-R1 (p55) and TNF-R2 (p75), on the cell surface. The aim of this study was first to investigate if there is alte...
Autores principales: | Maddahi, Aida, Kruse, Lars S, Chen, Qing-Wen, Edvinsson, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177895/ https://www.ncbi.nlm.nih.gov/pubmed/21871121 http://dx.doi.org/10.1186/1742-2094-8-107 |
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