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Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3

BACKGROUND: Extravasation of circulating cancer cells is a key event of metastatic dissemination that is initiated by the adhesion of cancer cells to endothelial cells. It requires interactions between adhesion receptors on endothelial cells and their counter-receptors on cancer cells. Notably, E-se...

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Detalles Bibliográficos
Autores principales: Porquet, Nicolas, Poirier, Andrée, Houle, François, Pin, Anne-Laure, Gout, Stéphanie, Tremblay, Pierre-Luc, Paquet, Éric R, Klinck, Roscoe, Auger, François A, Huot, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177907/
https://www.ncbi.nlm.nih.gov/pubmed/21722370
http://dx.doi.org/10.1186/1471-2407-11-285