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Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles

BACKGROUND: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial. This study sought to investigate whether a heterologous pr...

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Detalles Bibliográficos
Autores principales: Bridge, Simon H, Sharpe, Sally A, Dennis, Mike J, Dowall, Stuart D, Getty, Brian, Anson, Donald S, Skinner, Michael A, Stewart, James P, Blanchard, Tom J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177910/
https://www.ncbi.nlm.nih.gov/pubmed/21899739
http://dx.doi.org/10.1186/1743-422X-8-429