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Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles
BACKGROUND: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial. This study sought to investigate whether a heterologous pr...
Autores principales: | Bridge, Simon H, Sharpe, Sally A, Dennis, Mike J, Dowall, Stuart D, Getty, Brian, Anson, Donald S, Skinner, Michael A, Stewart, James P, Blanchard, Tom J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177910/ https://www.ncbi.nlm.nih.gov/pubmed/21899739 http://dx.doi.org/10.1186/1743-422X-8-429 |
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