Using Simple Donors to Drive the Equilibria of Glycosyltransferase-Catalyzed Reactions

We report the ability of simple glycoside donors to drastically shift the equilibria of glycosyltransferase-catalyzed reactions, transforming NDP-sugar formation from an endo- to an exothermic process. To demonstrate the utility of this thermodynamic adaptability, we highlight the glycosyltransferas...

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Detalles Bibliográficos
Autores principales: Gantt, Richard W., Peltier-Pain, Pauline, Cournoyer, William J., Thorson, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177962/
https://www.ncbi.nlm.nih.gov/pubmed/21857660
http://dx.doi.org/10.1038/nchembio.638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177962/
https://www.ncbi.nlm.nih.gov/pubmed/21857660
http://dx.doi.org/10.1038/nchembio.638

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