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Using Simple Donors to Drive the Equilibria of Glycosyltransferase-Catalyzed Reactions
We report the ability of simple glycoside donors to drastically shift the equilibria of glycosyltransferase-catalyzed reactions, transforming NDP-sugar formation from an endo- to an exothermic process. To demonstrate the utility of this thermodynamic adaptability, we highlight the glycosyltransferas...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177962/ https://www.ncbi.nlm.nih.gov/pubmed/21857660 http://dx.doi.org/10.1038/nchembio.638 |