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The tRNA synthetase paralog PoxA modifies elongation factor-P with (R)-β-lysine

The lysyl-tRNA synthetase paralog PoxA modifies elongation factor P (EF-P) with α-lysine at low efficiency. Cell-free extracts contained non-α-lysine substrates of PoxA that modified EF-P by a change in mass consistent with β–lysine, a substrate also predicted by genomic analyses. EF-P was efficient...

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Detalles Bibliográficos
Autores principales: Roy, Hervé, Zou, S. Betty, Bullwinkle, Tammy J., Wolfe, Benjamin S., Gilreath, Marla S., Forsyth, Craig J., Navarre, William W., Ibba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177975/
https://www.ncbi.nlm.nih.gov/pubmed/21841797
http://dx.doi.org/10.1038/nchembio.632