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Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge

To test the potential for parainfluenza virus 5 (PIV5)-based vectors to provide protection from vaccinia virus (VACV) infection, PIV5 was engineered to express secreted VACV L1R and B5R proteins, two important antigens for neutralization of intracellular mature (IMV) and extracellular enveloped (EEV...

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Detalles Bibliográficos
Autores principales: Clark, Kimberly M., Johnson, John B., Kock, Nancy D., Mizel, Steven B., Parks, Griffith D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177979/
https://www.ncbi.nlm.nih.gov/pubmed/21885079
http://dx.doi.org/10.1016/j.virol.2011.08.005