Cargando…

The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site

Both cellular environmental factors and chemical modifications critically affect the properties of nucleic acids. However, the structure and stability of DNA containing abasic sites under cell-mimicking molecular crowding conditions remain unclear. Here, we investigated the molecular crowding effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujimoto, Takeshi, Nakano, Shu-ichi, Miyoshi, Daisuke, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178115/
https://www.ncbi.nlm.nih.gov/pubmed/21949901
http://dx.doi.org/10.4061/2011/857149