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Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

OBJECTIVE: Chronic exercise and obesity both increase intramyocellular triglycerides (IMTGs) despite having opposing effects on insulin sensitivity. We hypothesized that chronically exercise-trained muscle would be characterized by lower skeletal muscle diacylglycerols (DAGs) and ceramides despite h...

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Detalles Bibliográficos
Autores principales: Amati, Francesca, Dubé, John J., Alvarez-Carnero, Elvis, Edreira, Martin M., Chomentowski, Peter, Coen, Paul M., Switzer, Galen E., Bickel, Perry E., Stefanovic-Racic, Maja, Toledo, Frederico G.S., Goodpaster, Bret H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178290/
https://www.ncbi.nlm.nih.gov/pubmed/21873552
http://dx.doi.org/10.2337/db10-1221