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Nrf2 Represses FGF21 During Long-Term High-Fat Diet–Induced Obesity in Mice
OBJECTIVE: Obesity is characterized by chronic oxidative stress. Fibroblast growth factor 21 (FGF21) has recently been identified as a novel hormone that regulates metabolism. NFE2-related factor 2 (Nrf2) is a transcription factor that orchestrates the expression of a battery of antioxidant and deto...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178292/ https://www.ncbi.nlm.nih.gov/pubmed/21852674 http://dx.doi.org/10.2337/db11-0112 |