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Obesity-Associated Hepatosteatosis and Impairment of Glucose Homeostasis Are Attenuated by Haptoglobin Deficiency

OBJECTIVE: Haptoglobin (Hp) is upregulated in both inflammation and obesity. The low chronic inflammatory state, caused by massive adipose tissue macrophage (ATM) infiltration found in obesity, and low adiponectin have been implicated in the development of insulin resistance and hepatosteatosis. The...

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Detalles Bibliográficos
Autores principales: Lisi, Simonetta, Gamucci, Olimpia, Vottari, Teresa, Scabia, Gaia, Funicello, Marcella, Marchi, Matilde, Galli, Giulia, Arisi, Ivan, Brandi, Rossella, D’Onofrio, Mara, Pinchera, Aldo, Santini, Ferruccio, Maffei, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178294/
https://www.ncbi.nlm.nih.gov/pubmed/21873550
http://dx.doi.org/10.2337/db10-1536