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Obesity-Associated Hepatosteatosis and Impairment of Glucose Homeostasis Are Attenuated by Haptoglobin Deficiency
OBJECTIVE: Haptoglobin (Hp) is upregulated in both inflammation and obesity. The low chronic inflammatory state, caused by massive adipose tissue macrophage (ATM) infiltration found in obesity, and low adiponectin have been implicated in the development of insulin resistance and hepatosteatosis. The...
Autores principales: | Lisi, Simonetta, Gamucci, Olimpia, Vottari, Teresa, Scabia, Gaia, Funicello, Marcella, Marchi, Matilde, Galli, Giulia, Arisi, Ivan, Brandi, Rossella, D’Onofrio, Mara, Pinchera, Aldo, Santini, Ferruccio, Maffei, Margherita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178294/ https://www.ncbi.nlm.nih.gov/pubmed/21873550 http://dx.doi.org/10.2337/db10-1536 |
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