Culturing Pancreatic Islets in Microfluidic Flow Enhances Morphology of the Associated Endothelial Cells

Pancreatic islets are heavily vascularized in vivo with each insulin secreting beta-cell associated with at least one endothelial cell (EC). This structure is maintained immediately post-isolation; however, in culture the ECs slowly deteriorate, losing density and branched morphology. We postulate t...

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Detalles Bibliográficos
Autores principales: Sankar, Krishana S., Green, Brenda J., Crocker, Alana R., Verity, Jocelyne E., Altamentova, Svetlana M., Rocheleau, Jonathan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178551/
https://www.ncbi.nlm.nih.gov/pubmed/21961048
http://dx.doi.org/10.1371/journal.pone.0024904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178551/
https://www.ncbi.nlm.nih.gov/pubmed/21961048
http://dx.doi.org/10.1371/journal.pone.0024904

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