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Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells
High-grade gliomas (World Health Organization grade III anaplastic astrocytoma and grade IV glioblastoma multiforme), the most prevalent primary malignant brain tumors, display a cellular hierarchy with self-renewing, tumorigenic cancer stem cells (CSCs) at the apex. While the CSC hypothesis has bee...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178553/ https://www.ncbi.nlm.nih.gov/pubmed/21961046 http://dx.doi.org/10.1371/journal.pone.0024807 |