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Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

High-grade gliomas (World Health Organization grade III anaplastic astrocytoma and grade IV glioblastoma multiforme), the most prevalent primary malignant brain tumors, display a cellular hierarchy with self-renewing, tumorigenic cancer stem cells (CSCs) at the apex. While the CSC hypothesis has bee...

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Detalles Bibliográficos
Autores principales: Lathia, Justin D., Gallagher, Joseph, Myers, Jay T., Li, Meizhang, Vasanji, Amit, McLendon, Roger E., Hjelmeland, Anita B., Huang, Alex Y., Rich, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178553/
https://www.ncbi.nlm.nih.gov/pubmed/21961046
http://dx.doi.org/10.1371/journal.pone.0024807