Expression of the RAE-1 Family of Stimulatory NK-Cell Ligands Requires Activation of the PI3K Pathway during Viral Infection and Transformation

Natural killer (NK) cells are lymphocytes that play a major role in the elimination of virally-infected cells and tumor cells. NK cells recognize and target abnormal cells through activation of stimulatory receptors such as NKG2D. NKG2D ligands are self-proteins, which are absent or expressed at low...

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Detalles Bibliográficos
Autores principales: Tokuyama, Maria, Lorin, Clarisse, Delebecque, Frederic, Jung, Heiyoun, Raulet, David H., Coscoy, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178570/
https://www.ncbi.nlm.nih.gov/pubmed/21966273
http://dx.doi.org/10.1371/journal.ppat.1002265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178570/
https://www.ncbi.nlm.nih.gov/pubmed/21966273
http://dx.doi.org/10.1371/journal.ppat.1002265

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