Overexpression of Cathepsin Z Contributes to Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma

The aim of this study was to characterize the oncogenic function and mechanism of Cathepsin Z (CTSZ) at 20q13.3, a frequently amplified region in hepatocellular carcinoma (HCC). Real-time PCR were used to compare CTSZ expression between paired HCC tumor and non-tumor specimens. CTSZ gene was stably...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Chen, Leilei, Li, Yan, Guan, Xin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178578/
https://www.ncbi.nlm.nih.gov/pubmed/21966391
http://dx.doi.org/10.1371/journal.pone.0024967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178578/
https://www.ncbi.nlm.nih.gov/pubmed/21966391
http://dx.doi.org/10.1371/journal.pone.0024967

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