Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance

The rise in type 1 diabetes (T1D) incidence in recent decades is probably related to modifications in environmental factors. Viruses are among the putative environmental triggers of T1D. The mechanisms regulating beta cell responses to viruses, however, remain to be defined. We have presently clarif...

Descripción completa

Detalles Bibliográficos
Autores principales: Colli, Maikel L., Nogueira, Tatiane C., Allagnat, Florent, Cunha, Daniel A., Gurzov, Esteban N., Cardozo, Alessandra K., Roivainen, Merja, Op de beeck, Anne, Eizirik, Decio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178579/
https://www.ncbi.nlm.nih.gov/pubmed/21977009
http://dx.doi.org/10.1371/journal.ppat.1002267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178579/
https://www.ncbi.nlm.nih.gov/pubmed/21977009
http://dx.doi.org/10.1371/journal.ppat.1002267

Ejemplares similares