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Galectin-3 Facilitates Cell Motility in Gastric Cancer by Up-Regulating Protease-Activated Receptor-1(PAR-1) and Matrix Metalloproteinase-1(MMP-1)

BACKGROUND: Galectin-3 is known to regulate cancer metastasis. However, the underlying mechanism has not been defined. Through the DNA microarray studies after galectin-3 silencing, we demonstrated here that galectin-3 plays a key role in up-regulating the expressions of protease-activated receptor-...

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Detalles Bibliográficos
Autores principales: Kim, Seok-Jun, Shin, Ji-Young, Lee, Kang-Duck, Bae, Young-Ki, Choi, Il-Ju, Park, Seok Hee, Chun, Kyung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178590/
https://www.ncbi.nlm.nih.gov/pubmed/21966428
http://dx.doi.org/10.1371/journal.pone.0025103