Effect of D222G Mutation in the Hemagglutinin Protein on Receptor Binding, Pathogenesis and Transmissibility of the 2009 Pandemic H1N1 Influenza Virus

Influenza viruses isolated during the 2009 H1N1 pandemic generally lack known molecular determinants of virulence associated with previous pandemic and highly pathogenic avian influenza viruses. The frequency of the amino acid substitution D222G in the hemagglutinin (HA) of 2009 H1N1 viruses isolate...

Descripción completa

Detalles Bibliográficos
Autores principales: Belser, Jessica A., Jayaraman, Akila, Raman, Rahul, Pappas, Claudia, Zeng, Hui, Cox, Nancy J., Katz, Jacqueline M., Sasisekharan, Ram, Tumpey, Terrence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178596/
https://www.ncbi.nlm.nih.gov/pubmed/21966421
http://dx.doi.org/10.1371/journal.pone.0025091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178596/
https://www.ncbi.nlm.nih.gov/pubmed/21966421
http://dx.doi.org/10.1371/journal.pone.0025091

Ejemplares similares