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Predicting Peptide Binding Affinities to MHC Molecules Using a Modified Semi-Empirical Scoring Function

The Major Histocompatibility Complex (MHC) plays an important role in the human immune system. The MHC is involved in the antigen presentation system assisting T cells to identify foreign or pathogenic proteins. However, an MHC molecule binding a self-peptide may incorrectly trigger an immune respon...

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Detalles Bibliográficos
Autores principales: Liao, Webber W. P., Arthur, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178607/
https://www.ncbi.nlm.nih.gov/pubmed/21966412
http://dx.doi.org/10.1371/journal.pone.0025055