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Predicting Peptide Binding Affinities to MHC Molecules Using a Modified Semi-Empirical Scoring Function
The Major Histocompatibility Complex (MHC) plays an important role in the human immune system. The MHC is involved in the antigen presentation system assisting T cells to identify foreign or pathogenic proteins. However, an MHC molecule binding a self-peptide may incorrectly trigger an immune respon...
Autores principales: | Liao, Webber W. P., Arthur, Jonathan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178607/ https://www.ncbi.nlm.nih.gov/pubmed/21966412 http://dx.doi.org/10.1371/journal.pone.0025055 |
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