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Meningitic Escherichia coli K1 Penetration and Neutrophil Transmigration Across the Blood–Brain Barrier are Modulated by Alpha7 Nicotinic Receptor

Alpha7 nicotinic acetylcholine receptor (nAChR), an essential regulator of inflammation, is abundantly expressed in hippocampal neurons, which are vulnerable to bacterial meningitis. However, it is unknown whether α7 nAChR contributes to the regulation of these events. In this report, an aggravating...

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Detalles Bibliográficos
Autores principales: Chi, Feng, Wang, Lin, Zheng, Xueye, Wu, Chun-Hua, Jong, Ambrose, Sheard, Michael A., Shi, Wei, Huang, Sheng-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178609/
https://www.ncbi.nlm.nih.gov/pubmed/21966399
http://dx.doi.org/10.1371/journal.pone.0025016